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This dose is maintained for at least four weeks to allow the body to adapt to the medication and to minimize gastrointestinal side effects
doi: 10.1016/j.cmet.2012.12.011 [DOI] [PMC free article] [PubMed] [Google Scholar] 50
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In experimental colitis models, ERS inhibitors such as sodium phenylbutyrate can significantly improve intestinal inflammation, indicating the important role of the ER stress PERK axis in IBD (101)
