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Such stress inducers are currently considered promising anticancer drugs [282]
Antioxidants are compounds in foods that prevent cell damage caused by free radicals
The SNPs may influence the efficacy of MTX and have been suggested as potential risk factors for enhanced MTX toxicity, even in low-dose regimens, based on previous researches [30]
Further, cell death mechanism, including pyroptosis and apoptosis have been causally linked to ROS induction [41, 42]
Am J Gastroenterol 2021;116:116-124
