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So far, it appears that their role depends on the H 2 O 2 levels within RBC: CAT is crucial for scavenging high exogenous and endogenous peroxide levels, GPx and Prx2 are important for scavenging low endogenous and low peroxide levels

Oral absorption in humans is unproven, but animal studies suggest possible systemic effects even with oral dosing6

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Given that that the aglycone is expected to primarily interact with the L1 in Ec GUS, we expect that the amino acid composition of L1 is responsible for this differential processing

It is important to note that, the previously predominant hypothesis of PGHS-2 mediated PGI 2 production in endothelial cells, which fitted well with PGHS-2-CVD link, was actually based on two major observations [98]