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J Neurochem 62:20452048

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Over the 8 residues spanning P4 to P4, it has 7 of 8 identical to the M pro site at the nsp12/nsp13 junction, with the only mismatch at the highly variable P3 position (Figure 1D), giving a near-perfect match to the M pro consensus

For instance, IF restored ETC proteins and normalized the oxygen consumption rates of Complex I and II in a rat model of pulmonary arterial hypertension (PAH) (Almuraikhy et al., 2024)

Research published in the Journal of Pharmacology and Experimental Therapeutics established that Dihexa treatment reversed scopolamine-induced cognitive deficits in rats, with treated animals performing comparably to healthy controls in Morris water maze spatial learning tasks