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Crian G, Moldovean-Cioroianu NS, Timaru D-G, Andrie G, Cinap C, Chi V

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It works by supporting the bodys natural signaling related to growth hormone pathways (rather than replacing growth hormone directly)

Folate deficiency can have serious side effects, so treatment (especially during early pregnancy) is important

Another strategy to improve sensitivity to leptin is to inhibit the autoinhibitory factors involved in leptin signaling, i.e., suppressor of cytokine signaling-3 and PTP1B