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The smaller population most likely reflects cells with high autofluorescence, as is often associated with phagosomes in macrophages
Environmental factors associated with neurodegeneration are diet, lifestyle, and chemical exposures such as metals mercury, cadmium, inorganic arsenic, and pesticides (e.g., deltamethrin, paraquat, dieldrin and rotenone) [3, 7], whereas environmental factors that have been shown to reduce the incidence of neurodegeneration are nicotine, caffeine, statins, post-menopausal hormonal treatment and non-steroidal anti-inflammatory drugs such as ibuprofen [3, 8]

(2003) Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice Biogerontology, 4(4):193-202

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