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In particular, a specific HPLC method coupled to ESI-MS and MS/MS analysis, including the evaluation procedure of the results, was set up as the analytical approach to monitor the compounds

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This interaction can likely be explained by the influence of S1P on phagosome formation

Linz+ Vit.C group: The animals were given vitamin C dissolved in normal saline at a dose of 100 mg/kg/day prior to administrating the dose of linezolid (dissolved in normal saline, 100mg/kg/day) via oral gavage for consecutive 14 days