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While the composition is mainly shaped by the hosts evolution, recent findings suggest that diet has a more significant impact on the metabolome than the microbiome

BAT is fully vascularized, which could provide transplanted islets with sufficient oxygen and nutrient

doi: 10.4103/02537613.132160 232 JooMKimHSKwonTHPalikheAZawTSJeongJHet al

doi: 10.1152/ajpcell.00130.2023 33 Van der StedeTVan de LoockATurielGHansenCTamariz-EllemannAUllrichMet al

These include nausea, vomiting, heartburn, and upset stomach, as well as occasional headache
