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The p67 phox subunit is constitutively phosphorylated in resting human PMNs and MEK1/2 in a PKC-, PI3K-, and p38MAPK-independent manner although the significance of this is unclear (Dang et al., 2011)

10.1093/mp/sss129 Mol Plant

This suggests a shift towards a more pro-oxidant form of NM in PD

Carere J, et al

Under type 2 (T2) conditions (IL-13 stimulation), human airway epithelial cells (HAECs) generate oxidized phospholipids under control of the 15 lipoxygenase 1 (15LO1) enzyme and its binding with phosphatidylethanolamine-binding protein 1 (PEBP1) (6)
