glutathione reductase nadph Schematic representation of the role of the enzyme Glutathione Reductase belongs to the homodimericFAD−disulfide oxidoreductases family The Role of Glutathione in

In preclinical research, this mechanism has been associated with selective apoptosis of senescent cells while preserving healthy cellular populations

10.1016/j.bbr.2010.11.013 66 DePoyL.DautR.BrigmanJ

J Agric Food Chem 53:18411856 [DOI] [PubMed] [Google Scholar] Ozbey F, Taslimi P, Gulcin I, Mara A, Goksu S, Supuran CT (2016) Synthesis, acetylcholinesterase, butyrilcholinesterase, carbonic anhydrase inhibitory and metal chelating properties of some novel diaryl ether

Notably, in addition to synoviocytes, synovial macrophages also have an important role in synovial inflammation of OA [137]

During the process of phospholipid hydroperoxide being reduced to the corresponding phospholipid alcohols, GSH acts as an electron donor, while glutathione disulfide (GSSG) is produced simultaneously (51)