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Psychiatry 34 LeeM.ChoT.JantaratnotaiN.WangY

125 ShaiN.SchuldinerM.ZalckvarE

In conclusion, we have identified a novel NADPH- and glutathione-dependent pathway through which TCA cycle activity impacts ER homeostasis

In the SELECT trial, patients did not enroll for the specific purpose of weight loss and received standard of care covering management of CV risk factors, including medical treatment and healthy lifestyle counseling, but without a specific focus on weight loss

therefore, cuproptosis through HMGB1 may be a key factor in sepsis-induced SAW
