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We found that cystamine had a strong protective effect against erastin-induced loss of cell viability, with a maximal protection (close to 100%) observed when 50 M cystamine was present (Fig

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Microenvironmental regulation of tumor progression and metastasis

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AP-1 is a core transcription factor that regulates the gene expression of essential enzymes involved in cartilage degradation, such as matrix metalloproteinase-13

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[DOI] [PubMed] [Google Scholar] 302.Janssen S., Laermans J., Verhulst P.J., Thijs T., Tack J., Depoortere I

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Dynamic changes in IRGs and cell cycle regulators, consistent with an adaptive strategy to resist iron overload and support survival, were observed

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