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Potential Side Effects in Skin Lightening Hydroquinone is a potent ingredient frequently utilized in the dermatology world for its skin-lightening abilities, particularly to brighten dark spots and melasma treatment

Tumor protein 53 (p53) can directly regulate cellular metabolism shifts by promoting mitochondrial oxidative phosphorylation (OXPHOS), leading to increased ROS production and is a positive regulator of ferroptosis

Whilst the long-term use of these biologic modifiers as long-term treatment is unknown, using them to control disease manifestations prior to HSCT is an attractive option (63, 64)

In these phases, SCI patients may suffer so-called spinal shock lasting 812 weeks, neurogenic shock lasting 34 months, and immunoinflammatory shock lasting 14 months [18,19,20]