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10.1104/pp.104.045625 Plant Physiol

To investigate the functional role of XKR8, we generated Xkr8 germline knockout (KO) mice (Extended Data Fig

5A, Supplementary data 2)

It can be a light twitch around the eye or a sudden knot in the leg

It's worth being precise about what "no side effects found" means here: this is not an absence of research, it is a consistent absence of a specific signal across the studies that did look for one
