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A wide range of adjuvants capable of triggering PRRs have been employed in preclinical cancer vaccine investigations, with some being evaluated in clinical trials (Hailemichael et al., 2013
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These findings support the rationale for frequent, low-dose supplementation strategies in healthy individuals, while also emphasising the need for personalised approaches in those with malabsorption syndromes (Bor et al., 2010)
