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Effects of fasudil on early atherosclerotic plaque formation and established lesion progression in apolipoprotein E-knockout mice

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The diminished function of key antioxidant enzymes and the overproduction of ROS/RNS can disrupt insulin signaling pathways, exacerbating hepatic lipid accumulation

Paradoxically, Kla modifications can also confer cytoprotective effects in specific cancer contexts
