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As a result, current hPS cell-based models face fundamental challenges in recapitulating the pathophysiology of late-onset and sporadic PD
Supersensitivity and Upregulation: occurs when a cell is deprived of its natural ligand for a long time, resulting in increased receptor expression over time and making the cell more sensitive to its ligand What is an example of supersensitivity
doi: 10.3389/fimmu.2022.905867 229 LeibundGut-LandmannS
G., Brown, T
Piracetam has the most robust evidence base, with multiple controlled trials showing benefits in age-related cognitive decline, stroke recovery, and memory
