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The research published on Karger [1] showed that obese Zucker rats treated orally with AOD 9604 had over 50% less body weight gain and increased lipolytic activity

Room temperature storage is suboptimal

To overcome the risks of genomic and chemical instability because of using nucleoside analogs, non-nucleoside DNMTs inhibitors have been tested as antitumor drugs in the last decade (Table 1)

Theoretically, the intracellular assimilation of folic acid via dihydrofolate reductase might enhance thymidylate synthetase by bypassing the methylfolate trap, thereby allowing cellular proliferation to progress temporarily
