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At steady state (Day 6), pre-dose baseline-corrected NAC plasma concentrations were approximately ten times higher than on Day 1 (mean SD 36.4 11.5 ng/mL vs

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doi: 10.1530/EC-14-0092

This has important implications in securing substrate mobilization and gluconeogenesis during fasting and explains the cardinal hypoglycemic symptoms in GHD and GHIS newborns in the absence of intrauterine growth retardation (IUGR)

Hyperlysinemia type II is an autosomal recessive disorder exhibiting variable phenotypes that may include intellectual disability, seizures, and delayed speech and language development