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Furthermore, translational challenges such as tissue targeting (e.g., bloodbrain barrier penetration), metabolic stability (e.g., optimization of CoQ analogs), and the need for predictive biomarkers underscore the importance of continued mechanistic studies to refine therapeutic strategies exploiting these emerging ferroptosis defense nodes
10.1016/j.semarthrit.2015.11.009 196 PengZ.SunH.BunpetchV.KohY.WenY.WuD.et al (2021a)
However, the reality is a bit more complex
Q: How long does barrier repair take
PMCID: PMC9124646
