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It is a mitochondrial-derived peptide encoded by mitochondrial DNA

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Care 5 , 152163 (2016)
These factors collectively contribute to myocardial cell injury and death, affecting both systolic and diastolic cardiac function while promoting adverse myocardial remodeling and eventual heart failure progression ( 2.2 Definition and characterization of ferroptosis The mechanisms of ferroptosis are illustrated in Figure 1
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