glutathione ten-membered ring Frontiers Steric and Electronic Effects Responsible
Description
Increased pro-inflammatory cytokines (IL-1, IL-6, TNF-)
The nucleophilicity depends upon several factors like basicity (p K a ), polarizability, and presence of non-bonded electrons on adjacent atom
[DOI] [PubMed] [Google Scholar] 132.Churuangsuk C., Kherouf M., Combet E., Lean M
doi: 10.1515/CCLM.2008.102
The conserved active site residue is found around position 10 of the signature motif SQPS
