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While humans can make a small amount of choline in the liver, its primarily provided by the diet

(2) the folate-independent remethylation pathway in which the methyl group is provided by betaine

Despite the promising results observed in preclinical and early clinical studies, the use of disulfiram in cancer treatment is not without challenges

doi: 10.1016/j.ejphar.2015.06.046 216 TakahashiMSatoTShinoharaFEchigoSRikiishiH

Use with caution in dogs with pre-existing epilepsy
