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doi: 10.1016/S0378-1119(97)00216-3 30 ChungHSLeeHJHwangSYChoiJHYooHJSeoJAet al
Several prior studies have proposed putative IC/BPS biomarkers from urine using metabolomics 17,18,19,20 , proteomics 21,22,23 , or bioactivity experiments 24,25,26,27
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5-Amino-1MQ is a first-in-class small molecule inhibitor designed to target Nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that acts as a master regulator of the cellular "metabolic drain."
