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that is, if 14 patients were treated for 4 years with metformin 850 mg t.d.s., one would develop vitamin B12 deficiency
A systematic review of physiologic rationales from clinical trials

References Orlovius AK, Thomas A, Schnzer W, Thevis M
In many cases, fatigue is likely the result of multiple overlapping factors

Q: Can high B12 cause nerve problems
