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19.2.2 Resistance Caused by Impaired Drug Uptake Drug uptake into cells occurs by one of the following mechanisms: (a) passive diffusion, in which the drug enters the cell by an energy- and temperature- independent process without interacting with specific constituents in the cell membrane

Acta Pharmacol Sin 30(5):501512 Wu X, Zhu Y, Yan H, Liu B, Li Y, Zhou Q et al (2010) Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells

Effectof glutathione-S-transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: randomised, placebo-controlled crossover study

Provision of a cellular source of NAD + which may be particularly important in preventing or inhibiting metabolic syndrome, protection of proteins from proteasomal degradation and enhancing protein translation by binding to mRNA represent emerging functions