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H.FakF.NookaewI.TremaroliV.FagerbergB.PetranovicD.et al (2012)

Conversely, if the cholesterol content of the cell is increased LDL receptor activity is decreased and the uptake of LDL by the cell is diminished

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Therefore, maintaining equilibrium among various fatty acid species (saturated, monounsaturated, and polyunsaturated) within membranes holds a position of critical importance, as any deviations from this equilibrium could lead to modifications in membrane integrity and cellular metabolic signaling