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For example, ROS drive hypoxia-inducible factor 1 (HIF1) mediated GLUT1 expression, hexokinase activity, and resultant glycolysis in response to low oxygen tension as part of the angiogenic response (27) The co-localization of neutrophil phosphofructokinase 2 with NOX2 leads to its activation, resulting in NADP+ production as its byproduct, facilitating an enhanced glycolytic rate

Researchers at Weill Cornell Medical College, the Icahn School of Medicine at Mount Sinai, Duke University and the Karolinska Institute in Stockholm, Sweden, also contributed to the work
These tend to be more selective than a haloacetyl for such a reaction

Hyperglycemia and dyslipidemia promote depressive symptoms by increasing systemic inflammation and reducing brain levels of serotonin (5-hydroxytryptamine, 5-HT) (Cai et al., 2022
