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Early diagnosis and lifelong treatment are crucial to prevent long-term health consequences

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In schizophrenia (SZ), Down Syndrome, and bipolar disorder (BD), increased brain insulin resistance and reduced IGF-1 signaling drive allostatic load/overload, leading to physiological dysregulation and the presentation of more severe symptoms throughout the body [44,45,46]

When liver cells are damaged or destroyed, they release stored cobalamin into the bloodstream
