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This usually involves: 1,000 mcg of B12 injected daily or every other day for 1-2 weeks Followed by weekly injections for a month 2

Evaluation of a spectrophotometric assay for the measurement of malondialdehyde and 4-hydroxy-alkenals in human spermatozoa: relationships with semen quality and sperm function

You will feel a difference in just a few days

Parul Sahni (2021) The screening and treatment of vitamin B12 deficiency

A lack of vitamin B12 doesnt directly lead to weight gain, however, so getting a B12 injection alone wont cause you to lose weight no matter how many times your doctor calls the injection a skinny shot