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The latter seems to be the most likely possibility since even custom-synthesized peptides that were substrate analogs (of GSH) failed to be effective as ChaC1 inhibitors

Higher MMP-9 serum levels have been related to Crohns disease relapses [113], while elevated plasma levels of MMP-2, -9 and -13 have been addressed as potential biomarkers of colorectal cancer [114,115,116]

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Muscle also releases IL-6 and IL-13, which increase hepatocyte insulin sensitivity

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