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Dilda et al., 2005b
University of Chicago Kidney Stone Evaluation and Treatment Program
We measured oxidative stress levels through malondialdehyde (MDA), a naturally occurring product of lipid peroxidation, and an established marker for oxidative stress
The formation of NAPQI is mediated by the cytochrome P450 (CYP) superfamily (Potter et al., 1973), with CYP1A2, 2D6, 2E1, and 3A4 isoforms as the major APAP oxidizing enzymes (Raucy et al., 1989
Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation
