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N., Ivanov, V

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demonstrated that Tom20 or Bax knockout effectively blocks ROS-induced pyroptosis, while antioxidant treatment significantly reduces Tom20 oxidation, Bax mitochondrial recruitment, and GSDME cleavage, further confirming that ROS serves as the central regulator of this signaling pathway (47)

Extensive research has explored the role of oxidative stress in the initiation and progression of AD

Patients in the treated group (n = 30) were given ALA in oral tablets of 200 mg, three times a day (600 mg/day) while patients in the control group (n = 30) were given cellulose starch, in similar tablets, 100 mg/day, three times a day