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Similarly, the concomitant downregulation of Adam19, a metalloproteinase closely associated with inflammation and oxidative stress-induced tissue remodeling 56 , further reinforces the hypothesis that APP treatment actively promotes endogenous antioxidant defenses and improves redox homeostasis rather than provoking nonspecific oxidative damage

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10.1155/2022/8983667 200 YuanQ.DuL.XuH.ZhangK.LiQ.ZhangH.et al (2022)

EMT boosts the invasion ability of CTCs, facilitating their movement into and out of blood vessels, thus selecting for more aggressive CTCs capable of metastasis

Fact: Every peptide has a specific "message" it sends to the body