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Additional evidence for a protective role of GPx1 can be in many other disease models, including stroke [106109], and neurodegeneration caused by trauma [114, 115], neurotoxins [116], and AD [123, 124]

At 12 months, all three treatment groups displayed improvements in the PBR of the sublingual arterial microvessels (marker of endothelial glycocalyx integrity using the GlycoCheck) and pulse wave velocity (marker of arterial stiffness)