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Levodopa remains the most effective agent for controlling motor symptoms, but its long-term use leads to motor complications, reduced efficacy, and treatment resistance (Kulisevsky, 2022
As discussed by Atalay and colleagues (Atalay et al
Toxicol Lett 161:96101, 2006
Regulation of KEAP1 expression by promoter methylation in malignant gliomas and association with patient's outcome
in this context, the production of ROS and RNS plays a crucial role in both the elimination of infected cells and cellular signaling [58,59]
