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2.4 ALKBH5-PRMT2- -catenin-GPX4 signaling pathway The ALKBH5-PRMT2--catenin-GPX4 axis is believed to play an important role in promoting LPS (lipopolysaccharide)-induced ferroptosis in microglial cells, providing new insights into the pathogenesis of depression

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C.BurgessS

In a study with a SARS-CoV-2-infected rhesus macaque, arginine supplementation to isolated peripheral blood mononuclear cells inhibited the release of pro-inflammatory cytokines, including IL-6 and TNF- [208]

The GD group exhibited higher levels of serum and muscle antioxidant enzymes along with upregulated expression of Nrf2 and its downstream targets (HO-1, NQO1) 24
