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Gastrointestinal problems at high doses High doses can cause gastrointestinal issues

1113 One had a positive 1:80 antinuclear antibody (ANA) titer, a liver biopsy significant for piecemeal necrosis (interface hepatitis) with lymphocyte and plasma cell infiltration, and a revised International Autoimmune Hepatitis Group (IAHG) score of 18 points, indicating definite autoimmune hepatitis (AIH)

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59 An RCT in adults with MASLD showed that high vitamin C intake in diet was associated with improved liver biomarkers including lower levels of ferritin and increased albumin