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AAO 2014)
10.1093/toxsci/kfp221 174 MoreyJ
Wei et al., 2015)
FAK is activated through phosphorylation by SRC family kinases, which have been shown to associate directly with c-MET [Ponzetto et al
Importantly, DNase I digestion, which degrades exosomal dsDNA, markedly suppressed STINGTBK1IRF3 signaling, confirming the functional contribution of exosomal dsDNA in HSC activation (Supplementary Fig
