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Choline, methionine, and inositol

Cellular magnesium status is unknown whilst magnesium levels within acceptable range however if magnesium levels are low then typically indicates significant cellular depletion and intervention recommended

Finally, the trial design could not have been appropriate to highlight, for example, a slowing of symptoms progression in early PD patients for too short follow-up or a wrong choice of primary endpoint measures

[Interesting fact treatment of OTC deficiency made headlines in 1999 when Jamie Gelsinger, an 18-year-old with mild OTC deficiency died during a gene therapy trial

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