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Prurigo pigmentosa following ketogenic diet and bariatric surgery: a growing association

Drug Metab Rev 36(34):511529 Abdelmegeed MA et al (2017) Role of CYP2E1 in mitochondrial dysfunction and hepatic injury by alcohol and non-alcoholic substances

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One of the most important concerns is that AX can be readily converted to astacene (3,3-dihydroxy-2,3,2,3-tetradehydro-,-carotene-4,4-dione) through oxidation in alkaline solutions in the presence of oxygen (Supplementary Figure S1) [67]

Timing can also play a role in how well you feel the effects