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Kiessling, M., Herchenhan, E

Clinical Update 12/07/2021 Can a Natural Colorant Cause Adverse Effects

Measurements of plasma C-peptide and proinsulin levels will help distinguish endogenous from exogenous hyperinsulinemia
Environmental factors, including mercury exposure and iron levels, can also interact with genetics

One possibility is that the GSH:GSSG ratio is already extremely high in some compartments, as discussed above, and so cannot be increased further in response to decreases in glutathione concentration
