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DH: Resources, Conceptualization, Writing review and editing

The latter provides strategies to support natural gut healing and a shift in GI homeostasis from potentially pathogenic to beneficial and congenital microbial ecologies or, at least, to restore gut eubiosis

A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response

The main challenges include overcoming financial and regulatory issues, especially for agents targeting hematological malignancies

Unlike all currently approved GLP-1 medications (semaglutide, tirzepatide, liraglutide, dulaglutide, exenatide), which are peptide-based and primarily administered by injection, orforglipron is a synthetic small molecule taken as a once-daily oral tablet