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The folate cycles intersection with the methionine cycle facilitates GSH production, and a deficiency in serine correlates with reduced GSH levels

Onuelu JE, Ben-Azu B, Adebayo OG, Fokoua AR, Nekabari MK, Ozah EO, Iwhiwhu P, Ajayi AM et al (2025) Taurine, an essential amino acid, attenuates rotenone-induced Parkinsons disease in rats by inhibiting alpha-synuclein aggregation and augmenting dopamine release

Compound heterozygosity for two defective alleles understandably results in more profound membrane skeleton deficiency and more severe disease

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& Itzkovitz, S
