glutathione peroxidase 4 selenium and Selenoproteins: Mechanisms, Health Functions, and Emerging Applications The Selenoprotein Glutathione Peroxidase 4:

Although the specific regulatory networks governing these features remain elusive, ferroptosis primarily encompasses three factors: aberrant iron ion metabolism, depletion of REDOX glutathione (GSH)/ GPX4/ cystine-glutamate transporter system (System Xc ), and dysregulated lipid peroxidation (9, 10)

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