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Additionally, although we have identified CAR18:0 as an immune-modulating metabolite enriched in butter-based HFD, we were unable to precisely determine the specific dietary component or metabolic process responsible for its enrichment in mice fed a butter-HFD or demonstrate that it was solely responsible for the dysfunction of CD8 T cells in vivo

Sacconi S, Trevisson E, Salviati L, Aym S, Rigal O, Redondo AG, Mancuso M, Siciliano G, Tonin P, Angelini C, Aur K, Lombs A, Desnuelle C

The safety and effectiveness of L-carnitine administration remain an issue for scientific investigation

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