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doi: 10.1172/jci.insight.161940 114 SzelesLTorocsikDNagyL

Senescence-induced oxidative stress causes endothelial dysfunction

By directly comparing hypoxia, HIF knockdown, HIF induction and PHD enzyme depletion, we and others have shown that PHD2 drives bone resorption by mature osteoclasts via induction of HIF-1 12,16,17,18

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7173 Carotid, cerebral, and coronary artery involvement has also been described
