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Similar content being viewed by others Introduction Glutamate is a direct precursor of various nitrogen-containing compounds, such as arginine, ornithine, proline, and glutathione, and most amino acids in living organisms are synthesized through the direct or indirect transfer of the amino group of glutamate 1
However, sustained overactivation can upregulate enzymes involved in lipid synthesis, increasing the accumulation of polyunsaturated fatty acids (PUFAs) and providing molecular targets for ferroptosis (87)
Alrashidi, M., Shahwan-Akl, L., James, J
