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7,12,13 To increase the efficacy of nose-to-brain delivery, nanoparticles have emerged as promising carriers because of their remarkable capacity to facilitate drug transportation

Ketamine (Ketalar) is a drug with wide ranging effects on the central nervous system due to its inhibition of glutamate receptors, known as N-methyl-D-aspartate (NMDA) receptors, in the brain
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FDA-approved with 15-17% body weight reduction demonstrated in Phase 3 STEP trials
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