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Description
A Mouse Model of Small-Vessel Disease that Produces Brain-Wide-Identified Microocclusions and Regionally Selective Neuronal Injury

Hepatology 2012
Caused up-regulation of lung tissue nuclear retinoic acid receptors (RARs) relative to vehicle-exposed mice, RAR (3.9-fold vehicle), RAR (3.3-fold), and RAR (3.7-fold) at 20.7 g/L

Amoretti A, Laydner H, Bergfeld W

[3] For confirmed deficiency with neurological involvement: 1 mg IM on alternate days until no further improvement, then 1 mg every two months urgent initiation is essential to prevent irreversible nerve damage
